reactive nitrogen species

Reactive nitrogen species ( RNS ) can induce chronic inflammation and insulin resistance when the individual was challenged with oxidative stress .

在氧化应激状态下，活性氮分子（RNS）能够诱导慢性炎症和胰岛素抵抗。

Nitration is a major modification caused by reactive nitrogen species in the condition of oxidative stress , one of the major product is 3-nitrotyrosine ( 3NT ) .

硝基化是氧化应激条件下由活性氮物质引起的主要蛋白质翻译后修饰之一，其中一种主要产物是3-硝基化酪氨酸（3NT）。

Modification Activating Mechanisms of Microsomal Glutathione S-transferase 1 by Reactive Nitrogen Species in Rat Primary Cultured Hepatocytes

活性氮对大鼠原代培养肝细胞微粒体GST1修饰激活机制

In the case of stimuli occurring such as infection and trauma , microglia become activated , and then they produce many immune effector molecules , including interleukin , tumor necrosis factor , interferon - γ, reactive nitrogen species , reactive oxygen species , etc.

小胶质细胞在受到感染、外伤等因素刺激后活化，并产生多种免疫效应分子，包括：白细胞介素、肿瘤坏死因子、干扰素γ、活性氮、活性氧等。

An appropriate amount of reactive oxygen / nitrogen species can act as signal molecules in cell physiological processes .

这些活性氧/氮族分子在适量的情况下可作为信号分子参与细胞的正常生理过程。

However , excessive reactive oxygen / nitrogen species can directly cause cell dysfunction and affect the transcriptional regulation of genes through the activation of its downstream signaling pathway .

但过量的活性氧/氮族分子却一方面可直接引起细胞功能障碍，另一方面通过激活其下游信号通路相关分子而影响细胞内基因的转录调控进而影响蛋白质表达异常。

Flavonoids can reduce LDL lipid peroxidation by scavenging reactive oxygen / nitrogen species , chelation of transition metal ions and sparing of LDL-associated antioxidants .

黄酮类可清除反应的氧、氮种类，螯合金属离子和节制低密度脂蛋白联合抗氧化作用，减少低密度脂蛋白氧化作用。